I only occasionally dabble in graphic design for fun, and even my pathetic, piddly little projects often lead me to compare 10 to 20 similar but subtly different fonts and weights in the same general design lineages before settling on one. I could easily imagine a more discerning eye considering and comparing
far more for a particular text setting.
Or I guess you could flip a coin a couple times to choose between Helvetica, Gotham, and Garamond and just call it a day.